By Volker ter Meulen, Michael Katz (auth.), W. Arber, W. Braun, R. Haas, W. Henle, P. H. Hofschneider, N. K. Jerne, P. Koldovský, H. Koprowski, O. Maaløe, R. Rott, H. G. Schweiger, M. Sela, L. Syruček, P. K. Vogt, E. Wecker (eds.)
Phenomena as varied as tuberculin sensitivity, not on time sensitivity to soluble proteins except tuberculin, touch allergic reaction, homograft rejection, experimental autoallergies, and the reaction to many microorganisms, were labeled as contributors of the category of immune reactions referred to as behind schedule or mobile allergic reaction. Similarities in time path, histology, and shortage of detectable circulating immunoglobulins symbolize those cell-mediated immune reactions in vivo. The kingdom of behind schedule or mobile allergy should be transferred from one animal to a different via sensitized residing lymphoid cells (CHASE, 1945; LANDSTEINER and CHASE, 1942; MITCHISON, 1954). The in charge phone has been defined via GOWANS (1965) as a small lymphocyte. Passive move has additionally been completed within the human with extracts of sensitized cells (LAWRENCE, 1959). The in vivo attribute of not on time allergy from which the category derives its identify is the behind schedule epidermis response. while an antigen is injected intradermally right into a formerly immunized animal, the common behind schedule response starts off to seem after four hours, reaches a height at 24 hours, and fades after forty eight hours. it really is grossly characterised via induration, erythyma, and sometimes necrosis. The histology of the behind schedule response has been studied by way of a variety of investigators (COHEN et al. , 1967; GELL and HINDE, 1951; KOSUNEN, 1966; KOSUNEN et al. , 1963; MCCLUSKEY et al. , 1963; WAKSMAN, 1960; WAKSMAN, 1962). at the beginning dilatation of the capillaries with exudation of fluid and cells occurs.
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Extra resources for Current Topics in Microbiology and Immunology: Ergebnisse der Mikrobiologie und Immunitatsforschung
VI. Synthesis of Phage DNA, and Conjugal DNA Transfer, in dna Mutants. 1. Synthesis of Phage DNA. . . . . . . . 2. DNA Transfer in Bacterial Conjugation . . . . . 3. Nature of the Functions Affected in dnaB and dnaG Mutants VII. dna Mutants and the Initiation of Chromosome Replication . 1. Regulation of Initiation . . . . . . . . 2. dna Mutants Defective in Initiation . . . . . . 3. Initiation Events Associated with Arrest of DNA Synthesis. VIII.
Neurol. Psychiat. ) 31, 685-700 (1934). DAYAN, A. , GOSTLING, J. V. , GREAVES, J. , STEVENS, D. , WOODHOUSE, M. : Evidence of a pseudomyxovirus in the brain in subacute sclerosing lencoencephalitis. Lancet 19671, 980-981DEITCH, A. : A method for the cytophotometric estimation of nucleic acids using methylene blue. J. Histochem. Cytochem. 12,451-461 (1964). EDGINGTON, T. , GLASSOCK, R. , DIXON, F. : Autologous immunecomplex pathogenesis of experimental allergic glomerulonephritis. Science 155, 1432-1434 (1967).
T. oJ' . •' . ~ , .... , .. ,. . ~ • . ••.. ", . ;. , ... . ,. • l) o •• •• . • tt:. '.. ~ : . f, '-'11 ,. , t. ~ ... , ' ' . --'III . '. ,t . t ~. ~ 'I" .. ~ . ' , . _ . >. ~ . ';JJ-~", .. " /l - . ' ! :,' •. :~ ~. ~J "'~". ",. ~'. ,', P. ' r~'r' L~ . ~:",:: . ' ~. W) . 4tA j_.. ~. ( ' . •.. ,1<'" • ,..... , "'~'" . ~, , . -. , '",. ;' • t .. ,. - ". , '. ~. " , Y.... "... ... _, ~ ... r I . ," ...... , . '" ~ r rJ " . , " '. t ". '.. a • . •If' .. Fig. 19. Papova virus·like particles.