Read e-book online Clinical Microbiology Made Ridiculously Simple (3rd Edition) PDF

By Mark Gladwin, Bill Trattler

A quick, transparent, thorough, and hugely relaxing method of medical microbiology, brimming with mnemonics, humor, precis charts and illustrations, from AIDS to "flesh-eating bacteria" to ebola, mad cow sickness, hantavirus, anthrax, smallpox, botulism, and so on. first-class Board assessment.

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STAPHYLOCOCCI Figure 5-6 P 2) Enterotoxins (heat stable): Exotoxins which cause food poisoning, resulting in vomiting and diarrhea. 3) Toxic Shock Syndrome toxin (TSST-1): This exotoxin is analogous to the pyrogenic toxin produced by Lancefield group A beta-hemolytic streptococci, but is far more deadly. This exotoxin causes toxic shock syndrome and is found in 20% of Staphylococcus aureaus isolates. These pyrogenic toxins are called superantigens and bind to the MHC class II molecules on antigen presenting cells (such as macrophages).

Bilateral hemorrhage into the adrenal glands occurs, which causes adrenal insufficiency. Abrupt onset of hypotension and tachycardia occurs, along with rapidly enlarging petechial skin lesions. Disseminated intravascular coagulation (DIC) and coma may develop. Death can occur rapidly (6-8 hours). 3) Meningitis: This is the most common form of meningococcal disease, usually striking infants < 1 year of age. Infants usually display nonspecific findings of an infection, including fever, vomiting, irritability, and/or lethargy.

STAPHYLOCOCCI Staphylococci are forever underfoot, crawling all over hospitals and living in the nasopharynx and skin of up to 50% of people. While at times they cause no symptoms, they can become mean and nasty. They will be one of your future enemies, so know them well. The 3 major pathogenic species are Staphylococcus aureus, Staphylococcus epidermidis, and Staphylococcus saprophyticus. It is extremely important to know how to differentiate staphylococci from streptococci because most staphylococci are penicillin G resistant!

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