By Franz Halberg (auth.), J. N. Mills (eds.)
A "biological clock" has now been inferred in such a lot of and such assorted organisms and tissues that even a precis of the extra fascinating and critical observations will be a tedious and encyclopaedic compila tion, whose bibliography might imagine a frightening dimension. it can even be obsolescent at the day of ebook. the recent titles showing within the per month lists are scattered via many journals, yet a brand new magazine committed solely to rhythm learn released its first factor in may well, 1970-the magazine of Interdisciplinary Cycle Research-and one other, Chronobiology, seems to be in 1973. during this quantity numerous authors were requested to check separate facets inside of their very own fields of analysis, within the wish that thereby the reader may well achieve an concept of the various instructions of energetic growth and be greater put to interrelate them than will be attainable after a extra exhaustive research of a restricted a part of the sphere. the end result is a chain of essays within which every one contributor has exercised his individuality in principles, sort and presentation, and, at a few issues, in vocabulary, even though the thesaurus incorporates a variety of phrases that have been particularly mostly used.
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Extra info for Biological Aspects of Circadian Rhythms
E. Klein, H. Bruner, H. Holtmann, H. Rehme, J. Stolze, W. D. Steinhoff and H. M. Wegmann, Circadian rhythm of pilots' efficiency and effects of multiple time zone travel. , 41, 125-131 (1970). 17. E. Haus and F. Halberg, Circadian acrophases of human eosinophil rhythm in patients with progressive or remitting rheumatoid arthritis, as compared to patients with osteoarthritis and healthy subjects. Rass. Neur. , 21, 227-234 (1967). 18. M. Garcia-Sainz and F. Halberg, Mitotic rhythms in human cancer, re-evaluated by electronic computer programs-evidence for temporal pathology.
Multiple cosinor quantifies internal timing of electrolyte rhythms in human saliva; data and analyses by C. Dawes. Level = Mesor. Cosinor plots for certain groups of patients differ with statistical significance from the cosinors of groups of healthy subjects. In any case, cosinors of properly sampled healthy individuals represent reference standards to which individual A and > values can be compared in diagnosis and treatment. Endeavours to restore normality of an altered A or > as well as M are justified in that we attempt to see thereby whether performance and/or health decrements are reduced or eliminated.
When exogenous and endogenous influences have a slightly different period, 'is in subjects living on a "day" of slightly over or under 24 h, both periods are usually seen in the final manifestations: one may for example find two urinary components of which one follows a 24-h cycle and the other a cycle whose period is equal to the artificial "day", or the same function may follow two periods simultaneously  leading to "beats". We appear here to have an internal clock and an exogenous rhythm out of synchrony and competing, rather than two separate clocks.