Microbiology

New PDF release: Becker USMLE Step 1 Immunology, Microbiology Version 1.3

By Cari Sloma Mary Ruebush

New. Becker USMLE Step 1 Immunology, Microbiology model 1.3 by way of Mary Ruebush, Cari Sloma : Product information: Becker USMLE Step 1 Immunology, Microbiology model 1.3 : layout: Paperback Product quantity: 2370000107299 UPC: 715875108590

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Extra resources for Becker USMLE Step 1 Immunology, Microbiology Version 1.3

Example text

Often, the most efficient of these cells are the resident dendritic cells of the epithelia, which transport their ingested antigens to the first available secondary lymphoid organ, where the activation of the lymphocytes begins. Pathways for Loading MHC Molecules With Peptides Since T lymphocytes can only "see" peptides that are presented to them by antigen-presenting cells, the processing of these fragments has a key role in determination of the ultimate immune response. 1 MHC Class 1 In all normal, nucleated cells, MHC class 1 molecules are synthesized in the endoplasmic reticulum.

48 Acute Inflammatory Response J Clinical -'Y~ Application - - - - - - - - - - - - - - - - - - - - - - - i Leukocyte adhesion deficiency type I (LAD 1) results from failure to prod uce CD18, which is the common (32 subunit of the (32 integrins (LFA·l family). (32 integrins are involved in leukocyte diapedesis, but also serve as receptors for C3b to promote opsonization and phagocytosis. Binding of (32 integrins to thei r ICAM ligands induces intracellular signaling that is important for a host of other cellular functions including cytokine production, cytotoxicity, apoptosis, and proliferation.

AU rights reserved. 2 Spleen The spleen is the largest lymphoid organ in the adult. It plays the dual role of removing aged or injured red blood cells in the red pulp and producing antibodies in the white pulp. 1 Architecture The spleen is supplied by the single splenic artery entering the capsule at the hilum . The arterioles branching from this become surrounded with lymphoid sheaths, which make up the white pulp. The arterioles terminate in sinusoids, which comprise the red pulp. Any antigen entering the blood is filtered out and responded to within the spleen.

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