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2 Problem: Abnormal Pubertal Development . . . . . . . . . 3 Male Factor Fertility Problems . . . . . . . . . . . . . . 4 Problem: Sexual Dysfunction . . . . . . . . . . . . . . 5 Problem: Male Contraception . . . . . . . . . . . . . . 6 Problem: Reproductive Tract Infections . . . . . . . . . . 7 Problem: Emergencies in Andrology . . . . . . . . . . . 8 Benign Lesions and Malignant Tumours of the Male Genital Tract . . . .

Close monitoring and yearly reevaluation of treatment are also important to minimize the adverse effects while maximizing the benefits. After reassignment surgery, including orchiectomy, hormone therapy must be continued. Continuous oestrogen therapy is required to avoid symptoms of hormone deprivation and, most importantly, to prevent osteoporosis. After bilateral oophorectomy, androgen therapy must be continued to maintain virilization and prevent osteoporosis (Van Kesteren 1998). 4 Surgical Sex Reassignment The procedures differ depending upon the direction of the sex change (Monstrey et al.

Whenever possible, researchers should consider obtaining consent for use of the samples in future studies. However, individuals must be free to consent for the use of their samples in the immediate specified research only, or for the use of these samples in the immediate specified research and also in future research, either of a specified or unspecified nature. The major consequence and major research benefit of giving human samples for research depend on whether the research results can be relayed back to the donor or not.

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